GM plants used for 90-days feeding studies

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GM plants used for 90-days feeding studies

GRACE reconsiders the quality and the information gain of animal feeding trials in general (i.e. no repetition of already conducted studies) by including additional conventional (conventional maize varieties) and positive controls (potatoes with high glycoalkaloid content).

The feeding trials will start in January 2013 and will follow OECD method TG 408 and the EFSA Recommendations on Repeated-dose 90-day oral toxicity study on whole food/feed in rodents (see EFSA, 2011).


Tested GM plants: two commercial varieties of maize MON810

  • DKC6667YG / Monsanto
  • PR33D48 / Pioneer Hi-Bred


Near isogenic lines of tested GM plants

  • DKC6666
  • PR32T16

Other conventional maize varieties:

  • DKC6717 (Monsanto)
  • DKC6815 (Monsanto)
  • PR32T83 (Pioneer Hi-Bred)
  • PR33W82 (Pioneer Hi-Bred)
  • SY Nepal (Koipesol Semillas)

Positive controls (potatoes):

  • Three experimental GM lines (developed by USDA-ARS) with modified levels of glycoalkaloids (high levels)
  • The parental conventional line Lenape (high glycoalkaloid level)
  • One experimental GM potato line (cisgenic line) resistant to Phytophthora (University Wageningen) and the parental conventional line

GRACE Database

Improving the availability of scientific information on GM plants


The database (currently under development) will contain quality assessed studies and conclusions on the health effects, socio-economic consequences and environmental impacts of GM plants.


More information ….

Stakeholder consultation

Stakeholder consultation on animal feeding studies and in-vitro studies for assessment of GMO impacts on human health.


3-4 December 2012, Vienna


More information …